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Detection of lowabundance, lowMW peptides remains difficult, complicating discrimination of functional translation from noise
Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, et al
Our finding of similar incidence of non-fatal cardiovascular outcomes with GLP1-RA compared to DPP4i is in line with the recently published FLOW study that randomized people with early to mid-stage CKD to semaglutide or placebo, which reported similar incidence of non-fatal myocardial infarction and non-fatal stroke across the semaglutide and placebo treated groups, despite a significantly reduced risk of major kidney disease events and all-cause death 44
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