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The original 2015 Cell Metabolism study demonstrated that intraperitoneal MOTS-c injections (5 mg/kg) in mice fed a high-fat diet prevented obesity and insulin resistance, with effects on fat mass, fasting glucose, and insulin sensitivity that rivaled pharmaceutical intervention [1]

These shifts in the redox state can modulate key signaling pathways that govern cell fate, such as NOTCH (Neurogenic locus notch homolog protein)

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If your insurance doesnt cover it or youre paying out of pocket, talk to your doctor about alternatives to Ozempic, Wegovy, and Rybelsus

beta Cell dysfunction during progression of metabolic syndrome to type 2 diabetes