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triagonism) on energy expenditure, glucose regulation, food intake, and weight loss in a well-established DIO mouse model in comparison to clinically relevant GLP1 receptor agonists [83]

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Potential pancreatitis risk : As with other GLP-1-based therapies, there is a theoretical concern regarding pancreatitis, though causality has not been firmly established in trials to date

Blood glucose monitoring is essential when GLP-1 therapy is combined with insulin or sulfonylureas due to increased hypoglycaemia risk

Balogh, G