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Cardiomyocytes and endothelial cells are major targets for SGLT2 inhibitors in the heart (Chen et al., 2022)

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These guidelines also emphasize: Prioritize protein (70-75g minimum daily) to prevent muscle loss Focus on nutrient-dense foods to meet vitamin and mineral needs Eat smaller, frequent meals (5-6 times daily) to manage side effects Limit simple carbohydrates and sugars that provide empty calories Monitoring Requirements : Regular tracking becomes even more important to ensure adequate nutrition despite reduced intake

A list of ongoing studies is in the Appendix at the end of this article