One of the initial discussions that is had when people are diagnosed is around weight management, because for people who are obese, it's been shown that weight reduction can ease symptoms
The NHS does not commission or fund either treatment
Improving care and promoting health in populations: standards of care in diabetes-2023
As all people with diabetes are at high risk of CVD, HF and CKD over time, real-world evidence and cost-effectiveness studies of GLP-1 RA and SGLT2i in broad populations would help to better target interventions to have the greatest impact on outcomes
Key takeaways Research shows mixed results on semaglutide's effect on testosterone, with some studies showing increases and others decreases
If tolerance is good and no concerning reactions occur, consider increasing to twice-daily application or moving to a 1 percent concentration