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In the laboratory it is typically supplied as a lyophilised (freeze-dried) acetate salt that is reconstituted before use

Individual consent was not necessary due to the retrospective design of the study

Development was discontinued because the Phase IIb trial of 536 subjects over 24 weeks failed to meet its primary efficacy endpoint

Treatment availability may vary by location

Lameness may manifest as the result of an acute traumatic injury, for example a tendon laceration, or as the result of repetitive cyclic loading leading to degeneration of tissue, for example cartilage damage leading to osteoarthritis in a joint