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This ensures a personalized approach to treatment from the outset

Digestive enzymes taken before meals and probiotics for long-term microbiome support are excellent complementary approaches

Ni W, Lu Y, Wang W

Quick Answer: Co-prescribing Rybelsus (semaglutide) and Januvia (sitagliptin) is generally not recommended in UK clinical practice due to overlapping incretin-based mechanisms that provide limited additional glycaemic benefit

However, the authors note that substantial weight loss can be accompanied by reductions in lean body mass, underscoring the need for further research into dosing strategies and interventions that preserve muscle while promoting fat loss

Zhou C, Zaman N, Li Y, Martinez-Arguelles DB, Papadopoulos V, Zirkin B, et al