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In many fish species, high dietary carbohydrate induced lower growth, excess lipid deposition, and decreased stress resistance 38,39,40

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Right, cell lysates from mock and FSP1HA Pfa1 cells treated with or without TAM for 48 h were used for the assay as shown by the immunoblot (FSP1, GPX4 and -actin)

Treatment of pre-existing obesity: animals with genetic mutations (ob/ob or db/db mice) causing obesity or high-fat diet-induced obesity at baseline

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