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Both compounds influence overlapping biological pathways, though their effects appear complementary rather than antagonistic
This article is for general information only and is not personal medical advice
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The first primary end point showed that 63% of patients treated with semaglutide achieved resolution of MASH with no worsening of liver fibrosis, compared with 34% of patients on the placebo
Importantly, the incidence of liver enzyme abnormalities was not higher in tirzepatide-treated patients compared to control groups
Clearly, markets are concerned about Novos ability to keep up the sales growth of its GLP-1 when an apparently superior treatment exists
