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The angiotensin-converting enzyme (ACE), secreted by lung and kidney, converts ANG I to ANG II, whereas the angiotensin-converting enzyme 2 (ACE2) further cleaves ANG II to ANG (1,7)

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As is the case with all intravenous infusions, febrile reactions, infections at the site of injection, venous thrombosis or phlebitis and extravasation may occur