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A 2019 meta-analysis by Wei et al 11 reviewed the results of 4 RCTs on the use of onabotulinumtoxinA for TN and noted a significant improvement in reported pain values in comparison with placebo, with an estimated number needed to treat of 1.9 to achieve a 50% reduction in pain intensity
Together, these compounds allow researchers to explore complementary mechanisms involved in metabolic health and longevity
It is also said to have antioxidant and anti-inflammatory properties.it, when used in skincare formulations, is typically added to serums, creams, or lotions to enhance the skin's elasticity, reduce the appearance of scars, and promote overall skin health
A more recent systematic review by Rubis and Juodzbalys 12 included 4 double-blind, placebo-controlled RCTs with 8- to 12-week follow-up