In last weeks confirmation hearing, Cassidy seemed to feel very critical of Schwartz in his line of questioning
Rather than describing outcomes in terms of symptom relief or treatment, investigators focus on mechanistic language such as changes in specific markers, pathways, or structural features
often included in weight loss programs
Gerald Zaltman and Robert Duncan , Strategies for Planned Change, p
Even with an omnivorous diet, a supply is not always assured
Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning