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Despite these limitations, the findings support recommending GLP-1RAs to facilitate weight loss and improve outcomes in CKD patients with obesity, even in the absence of diabetes

Results We included 1,647,238 patients who were prescribed a GLP-1 RA between January 2024 and July 2025, with 6,059,445 total GLP-1 RA prescriptions during this period

In practice, that means optimized layouts, readable typography, and interface elements that feel responsive without distracting animations or cluttered overlays

This doesnt mean the medication isnt working

You may need to stay on a weight loss drug long-term, or even indefinitely, and pair it with lifestyle changes like diet and exercise to achieve more significant and sustainable weight loss

For severe persistent abdominal pain (especially with vomiting), contact your GP urgently, call NHS 111, or go to A&E