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Maiti A, MBBS, DiNardo CD, MD, MSCE, Rausch CR, PharmD, Pemmaraju N, MD, Garcia-Manero G, MD, Ohanian M, DO, Daver N, MD, Issa GC, MD, Borthakur G, MD, Ravandi F, MBBS, Alvarado Y, MD, Kadia TM, MD, Short NJ, MD, Jabbour EJ, MD, Montalban-Bravo G, MD, Jain N, MD, Kornblau SM, MD, Masarova L, MD, Wierda WG, Sasaki K, MD, PhD, Takahashi K, MD, PhD, Yilmaz M, MD, Burger JA, MD, PhD, Estrov ZE, MD, Verstovsek S, MD, PhD, Andreeff M , MD, PhD, Bose P, MD, Ferrajoli A, MD, Thompson PA, Montalbano K, Vaughan K, RN, Bivins CA, RN, Pierce SA, BSN, BA, Qiao W, PhD, Ning J, Welch J, PhD MD, Kantarjian H, MD, Konopleva M, MD, PhD

WMD = 0.21 kg/m 2 , 95% CI 1.31 to 0.88, P = 0.7, I 2 = 0.0%)

Treatments with a family of lipid-lowering drugs known as fibrates (e.g., fenofibrate, bezofibrate) have been associated with an increased excretion of betaine in the urine and a rise in homocysteine concentration in the blood of patients with diabetes mellitus or metabolic syndrome (125, 126)

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