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Introduction# CagriSema (cagrilintide + semaglutide, Novo Nordisk) and tirzepatide (Eli Lilly) represent the pinnacle of next-generation obesity pharmacotherapy, both achieving approximately 20% weight loss through different dual-mechanism approaches

Chemical Name: (2S,3S)-N-(6-amino-6-oxohexyl)-2-[[(2S)-2-(hexanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanamide Dihexa is a synthetic peptide compound known for its unique structure and potent activity as a small-molecule modulator in neurobiological research

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This article shows that long-acting GIP decreases body weight and food intake via CNS GIPR signalling

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