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Other conditions that make Vitamin B12 absorption more difficult are: Weight loss surgery or another operation that removed part of your stomach Heavy drinking Taking acid-reducing medication for a long time Certain health issues may also lead to the development of vitamin B12 deficiency such as atrophic gastritis, pernicious anemia, Crohns disease, celiac disease, immune system disorders, Graves disease and lupus

Causes of deficiency include: Insufficient intake Malabsorption in gastrointestinal diseases Increased requirements during pregnancy Antiepileptic drugs (phenytoin, primidone, phenobarbital) may decrease FA absorption, presumably by inhibiting the formation of monoglutamine- folic acid Inhibition of dihydro-folic acid reductase (e.g., by methotrexate) depresses the formation of the active species, tetrahydro-folic acid Symptoms of deficiency are: megaloblastic anemia mucosal damage Therapy of folic acid deficiency Therapy consists in oral administration of Folic Acid or folinic acid when deficiency is caused by inhibitors of dihydroFAreductase

Safe if prescribed Bon-B12 2500 mcg Injection should be used in children only if prescribed by a doctor

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