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found that activating transcription factor 4 (ATF4) binds to the ASNS gene promoter through Zinc Finger and BTB domain-containing protein 1 (ZBTB1) to promote ASNS transcription in drug-resistant T-cell leukemia
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In GFP-LC3 transgenic mice overexpressing LC3, which are used to manipulate autophagy and model pancreatitis, the number and size of autophagic vacuoles in the pancreas are significantly greater than those in wild-type mice, which is correlated with pancreatitis severity
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