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Schaub, J., Van Hoof, F
Meanwhile: Systemic reviews still note that trailed human data are sparse, and most benefits remain in the preclinical promise category
Lm trng da ton thn, tr nm, tn nhang t su bn trong Lm chm qu trnh lo ha t nhin do tui tc, gip tr ha ln da, bo v da khe mnh trc cc tc nhn gy hi cho da
In pathological conditions such as cancer, dysregulation of these mechanisms leads to vascular hyper-permeability that in turn may exert direct effects on the tumor microenvironment including increased interstitial pressure and impaired therapeutic delivery [127]
It is worth being precise here: engaging three pathways simultaneously is a rational design hypothesis, but how those combined effects translate into durable, safe clinical outcomes in patients is exactly what the ongoing trials are intended to determine
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