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The loss of HNF1A and FXYD2 may induce membrane hyperpolarization, thereby impairing insulin secretiona mechanism relevant to both maturity-onset diabetes of the young type 3 (MODY3) and T2D (Weng et al., 2023)

vocalizing, grooming) in impaired and non-impaired mice

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This is substantiated by the pharmacokinetic data showing that L-carnitine co-injection did not alter the plasma concentration of colistin