Understanding the full landscape of delivery options helps researchers evaluate where intranasal retatrutide fits
doi:10.1016/j.spen.2013.10.008CrossRefGoogle ScholarPubMed Krhenbhl, S, Brandner, S, Kleinle, S, Liechti, S, Straumann, D
The most common side effects are GI-related
Some researchers have hypothesized that GLP-1 receptor stimulation might promote pancreatic duct cell proliferation or increase pancreatic enzyme secretion, but animal studies have not consistently demonstrated these effects at therapeutic doses
Starting doses are intentionally subtherapeutic for weight loss
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis