One important context point the headline numbers miss: in STEP-1, while absolute lean mass dropped, lean body mass *as a proportion of total body mass* actually rose by roughly 3 percentage points
People with obesity are more likely to have cancer and cardiovascular disease, and recent research has shown that people who use GLP-1 analogues could have a lower risk of both
However, body weight remained significantly lower in these groups throughout the 21-day study, suggesting that cagrilintides weight-lowering action extends beyond acute appetite suppression
A study published in 2021 demonstrated that individuals taking tirzepatide experienced up to 22.5% weight loss, which is significantly higher than the 15-20% weight loss reported in studies on semaglutide
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Wait 35 days before initiating dosing