These combinations are largely untested in clinical trials
A review of laser and light therapy in melasma
Looking ahead, the key strategies for product innovation and differentiation are likely to focus on five main directions: expanding the therapeutic indications, achieving precision treatment with multiple biological targets, optimizing the clinical application of drug combinations, developing new formulations of oral medications, and extending the duration of drug action
doi: 10.1155/2018/1578320 37 DuewellP.KonoH.RaynerK
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Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment