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It seems that any decrease from a given SSBW is seen as a danger for the body to survive, so the genes reflecting the respective counterregulatory responses may not have drifted and may still be fully active, different from the genes that may originally have protected us from excessive weight gain

These shifts are incredibly effective for weight loss and metabolic health, but they also explain why some people experience side effects, especially in the first few weeks

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It also shows potential in eliminating the pro-inflammatory phenotype of senescent cells and improving the functional microenvironment of tissues

Excitingly, this emerging field may soon yield other discoveries that could redefine our understanding of related conditions