4.1.2 Clinical applications and implications This meta-analysis brings to light various clinically relevant aspects that must be considered from a public health perspective: Reassurance in Clinical Decision-Making As part of our results, it is evident that GLP-1 RAs do not increase the risk for gastrointestinal cancers and may even have protective effects for colorectal and liver cancers
People talk about nausea all the time
This metabolic starvation is a primary driver of the cognitive dysfunction patients experience
Some studies have also reported hypoglycemia (low blood sugar) due to its insulin-like effects
The seven-day interval is not arbitrary
Different strategies were used to improve the peptide half-life including sequence modifications (exenatide, lixisenatide) 36,37 , conjugation to molecules with propensity to bind albumin (liraglutide, semaglutide) 36,37 , fusion to large proteins (albiglutide, dulaglutide, efpeglenatide) 36,37 , side chain cross linking 38,39 , and -residue replacement 40,41,42 (Fig
