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In detail, the experimental group fed with 2.5% (w/v) BP for 20 and 30 days showed the greatest protection against the described pathogen
This proposed mechanism has been directly validated in animal models where the surgically severed vagus nerve attenuated anxiety- and depression-like behaviors in mice after oral antibiotic administration, providing direct evidence for neuropsychiatric effects induced by antibiotics through the gutbrain axis (Joo et al., 2023)
Both mouse primary cortical neurons (10 or 20 M for 3 or 6 h) and a triple-transgenic AD mouse model treated with SF (56.4 or 282 mol/kg/day for 6 days/week for 8 weeks) exhibited enhanced brain-derived neurotropic factor (BDNF) expression, crucial for neuronal survival and synaptic plasticity, suggesting a potential epigenetic mechanism for SFs neuroprotective effects (61)
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and Nova Southeastern University
