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Proper dose titration was key to minimizing side effects (Jastreboff et al., 2023)

For someone who is genuinely low in B12, correcting that deficiency can absolutely help with fatigue

and in July 2024, the FDA approved Kisunla (donanemab) for early symptomatic Alzheimers, based on evidence of reduced clinical decline and a limitedduration regimen tied to amyloid plaque removal

Kham 45 F 1632 Harleysvi PA 59:15 2:09:19 2:09:00 9:51 1947 45 891 Veronica Harvey 50 F 2505 Macungie PA 58:51 2:10:11 2:09:00 9:51 1948 112 892 Jill Sperry 45 F 3740 Allentown PA 1:03:00 2:10:36 2:09:02 9:51 1949 141 1057 Bryan Klansek 30 M 2737 Breinigsv PA 58:58 2:10:33 2:09:04 9:52 1950 137 1058 Ed Coringrato 54 M 2030 Fogelsvil PA 1:02:52 2:11:35 2:09:04 9:52 Page 66 St Luke's Lehigh Valley HALF-MARATHON/5k ALLENTOWN, PA APRIL 29, 2012 USATF CERT# PA10015 WB UNOFFICIAL Results by Queen City Timing Services HALF-MARATHON Place Div Gend Name Age G Bib City St Halfspl Gun Net Pace ===== ==== ==== =================== === = ===== ========= == ======= ======= ======= ===== 1951 22 893 Marianne Kellner 58 F 2693 Coaldale PA 1:01:42 2:10:24 2:09:08 9:52 1952 64 1059 Joe Sopko 56 M 3733 Macungie PA 1:01:18 2:10:34 2:09:09 9:52 1953 151 894 Brandie Kessler 29 F 2717 Pottstown PA 1:03:00 2:10:42 2:09:09 9:52 1954 113 895 Mary Beth Kowalski 48 F 2788 Clarks Su PA 1:00:47 2:10:39 2:09:11 9:52 1955 161 896 Tara Griffiths 35 F 1165 Easton PA 1:00:07 2:10:39 2:09:11 9:52 1956 4 1060 Thomas Nuzzalo 73 M 1381 Pottstown PA 1:00:43 2:10:14 2:09:12 9:52 1957 92 1061 Jeffrey Marx 29 M 2997 Scranton PA 1:03:02 2:10:39 2:09:14 9:52 1958 162 897 Charise Jones 36 F 1211 Easton PA 57:18 2:09:57 2:09:16 9:53 1959 167 1062 Abraham Assad 47 M 1709 Allentown PA 2:11:35 2:09:16 9:53 1960 199 1063 Chris Fenstermaker 40 M 2247 Palmerton PA 1:03:15 2:10:50 2:09:18 9:53 1961 142 1064 Rob Pretopapa 31 M 657 allentown pa 57:30 2:09:36 2:09:18 9:53 1962 143 1065 Ty Bowman 31 M 1865 Dallas PA 1:02:27 2:11:25 2:09:18 9:53 1963 162 898 Katarzyna Strojwas 34 F 805 Nazareth PA 1:00:34 2:10:15 2:09:19 9:53 1964 39 1066 Daniel Church 21 M 1989 Washingto NJ 1:02:34 2:11:55 2:09:21 9:53 1965 75 899 Brittany Martucci 22 F 2993 Gilbert PA 1:03:18 2:11:02 2:09:24 9:53 1966 150 900 Michele Lefchak 44 F 2871 Doylestow PA 1:01:56 2:12:11 2:09:24 9:53 1967 151 901 Kim Malone 43 F 2967 Doylestow PA 1:01:57 2:12:11 2:09:24 9:53 1968 152 902 Marianne Williams 44 F 4027 Rydal PA 1:02:56 2:13:03 2:09:25 9:53 1969 163 903 Beth Franceschino 37 F 2299 Phillipsb NJ 59:36 2:10:24 2:09:25 9:53 1970 168 1067 Steven Heller 49 M 333 Easton PA 59:22 2:10:46 2:09:27 9:53 1971 200 1068 Alejandro Nieto 41 M 3254 Stewartsv NJ 1:06:32 2:11:40 2:09:29 9:53 1972 153 904 Kathleen Regan 43 F 674 Lansdale PA 59:34 2:10:29 2:09:31 9:54 1973 154 905 Ingrid Gerber 44 F 2361 Allentown PA 1:03:05 2:11:02 2:09:33 9:54 1974 93 1069 Chris Paone 29 M 3333 Peckville PA 1:02:28 2:12:04 2:09:36 9:54 1975 46 906 Linda Weiss 51 F 3991 East Stro PA 1:03:32 2:11:56 2:09:37 9:54 1976 94 1070 David Goochee 26 M 2393 Southampt PA 1:01:23 2:11:09 2:09:37 9:54 1977 114 907 Elizabeth Gertz 49 F 2365 Hellertow PA 1:03:02 2:11:14 2:09:38 9:54 1978 138 1071 Warren Stevens 52 M 3782 Allentown PA 59:47 2:12:52 2:09:38 9:54 1979 152 908 Diana Mantore 28 F 2971 Macungie PA 1:02:58 2:11:14 2:09:38 9:54 1980 76 909 Maria Izzi 24 F 2628 Southampt PA 1:01:21 2:11:12 2:09:40 9:54 Page 67 St Luke's Lehigh Valley HALF-MARATHON/5k ALLENTOWN, PA APRIL 29, 2012 USATF CERT# PA10015 WB UNOFFICIAL Results by Queen City Timing Services HALF-MARATHON Place Div Gend Name Age G Bib City St Halfspl Gun Net Pace ===== ==== ==== =================== === = ===== ========= == ======= ======= ======= ===== 1981 164 910 Leslie Zapp 37 F 928 Walnutpor PA 1:01:12 2:10:49 2:09:41 9:54 1982 165 911 Jill Italiano 38 F 2627 Stamford CT 1:02:54 2:10:48 2:09:43 9:55 1983 23 912 Nancy Carr 58 F 1959 Coopersbu PA 1:04:18 2:11:34 2:09:43 9:55 1984 166 913 Laura Kane 38 F 2671 Sellersvi PA 1:02:42 2:11:44 2:09:43 9:55 1985 169 1072 Myles Bartos 38 M 1755 Sellersvi PA 1:02:41 2:11:46 2:09:45 9:55 1986 40 1073 Donnie Pierce 24 M 3375 Pennsburg PA 59:25 2:10:55 2:09:46 9:55 1987 65 1074 Donald Evans 58 M 224 Sellersvi PA 1:01:29 2:11:31 2:09:46 9:55 1988 167 914 Kristen Delaney 36 F 2101 Pottstown PA 1:03:09 2:11:18 2:09:46 9:55 1989 169 1075 Gary Delp 49 M 4120 Lansdale PA 1:01:03 2:11:18 2:09:46 9:55 1990 66 1076 Paul Schaffer 56 M 3570 allentown pa 1:01:29 2:11:31 2:09:46 9:55 1991 95 1077 Matt Shiminsky 26 M 1488 Bridgewat NJ 1:04:09 2:11:49 2:09:49 9:55 1992 155 915 Jennifer Wieand 40 F 4010 Center Va PA 1:04:37 2:09:49 2:09:49 9:55 1993 163 916 Adrienne Ibarra 31 F 1197 Northampt PA 1:06:51 2:12:28 2:09:49 9:55 1994 14 917 Jacqueline Viens 17 F 3942 Kennett S PA 1:03:00 2:11:16 2:09:50 9:55 1995 115 918 Jocelyn Lowe 46 F 1302 Kennett S PA 1:03:01 2:11:17 2:09:51 9:55 1996 168 919 Randi Brogan 36 F 1899 Highland NY 59:54 2:11:14 2:09:54 9:55 1997 24 920 Debra Klepeiss 57 F 2746 Coplay PA 1:06:51 2:12:33 2:09:54 9:55 1998 116 921 Anne Haag 47 F 2461 Quakertow PA 1:03:45 2:12:51 2:09:55 9:55 1999 77 922 Tegan Hanlon 21 F 1174 Allentown PA 1:03:21 2:11:48 2:09:55 9:55 2000 25 923 Marisa Leva 58 F 2891 Glen Mill PA 1:02:49 2:11:21 2:09:58 9:56 2001 170 1078 Jonathan Shimmons 48 M 3655 Chevy Cha MD 1:04:42 2:12:19 2:10:01 9:56 2002 117 924 Mary Miller 45 F 964 Doylestow PA 1:00:09 2:10:33 2:10:03 9:56 2003 169 925 Tiffany Blanton 38 F 940 Doylestow PA 1:00:09 2:10:34 2:10:03 9:56 2004 47 926 Nancy Tretter-Long 50 F 3896 Pipersvil PA 1:00:53 2:13:11 2:10:04 9:56 2005 139 1079 Melchiore Vernace 51 M 3939 Doylestow PA 1:02:29 2:11:48 2:10:04 9:56 2006 140 1080 David Smith 53 M 3698 Doylestow PA 1:02:30 2:11:48 2:10:04 9:56 2007 171 1081 Andrew Park 48 M 3337 Branchbur NJ 1:05:04 2:12:23 2:10:06 9:56 2008 170 927 Melissa Kaufman 38 F 4153 Throop PA 1:05:15 2:13:06 2:10:09 9:57 2009 170 1082 Thomas Payne 35 M 3350 Vienna VA 1:03:02 2:12:44 2:10:09 9:57 2010 78 928 Laura Provenzano 23 F 3412 Kingston PA 1:02:26 2:12:43 2:10:09 9:57 Page 68 St Luke's Lehigh Valley HALF-MARATHON/5k ALLENTOWN, PA APRIL 29, 2012 USATF CERT# PA10015 WB UNOFFICIAL Results by Queen City Timing Services HALF-MARATHON Place Div Gend Name Age G Bib City St Halfspl Gun Net Pace ===== ==== ==== =================== === = ===== ========= == ======= ======= ======= ===== 2011 171 929 Joelle Smith 37 F 3705 Macungie PA 1:03:58 2:13:04 2:10:09 9:57 2012 48 930 Teena Renfrow 50 F 1431 Bethlehem PA 1:01:19 2:10:41 2:10:11 9:57 2013 144 1083 Robert Brasko 34 M 1875 Hellertow PA 1:05:25 2:12:55 2:10:13 9:57 2014 118 931 Robin Snyder 46 F 3722 Dalton PA 1:01:09 2:11:51 2:10:14 9:57 2015 164 932 Andrea Myers 31 F 1373 New Freed PA 1:01:34 2:10:35 2:10:16 9:57 2016 79 933 Abby Barnhart 24 F 1740 Bethlehem PA 1:03:23 2:11:49 2:10:18 9:57 2017 165 934 Elizabeth Wiggins 30 F 4012 Bethlehem PA 1:03:24 2:11:49 2:10:18 9:57 2018 156 935 Ami Tarburton 42 F 3843 Green Lan PA 59:41 2:11:29 2:10:19 9:57 2019 80 936 Stephanie Schoenly 22 F 3594 Bechtelsv PA 59:44 2:11:53 2:10:19 9:57 2020 153 937 Megan Eddinger 25 F 1103 Middletow DE 58:36 2:11:07 2:10:19 9:57 2021 154 938 Ashley Tranter 29 F 3892 Bethlehem PA 1:01:46 2:11:27 2:10:19 9:57 2022 172 939 Linay Richards 38 F 3473 Dublin PA 1:00:25 2:12:33 2:10:23 9:58 2023 49 940 Sharon Sechrist 50 F 3613 allentown pa 1:05:00 2:11:42 2:10:24 9:58 2024 15 941 Kristen Kauffman 18 F 2678 Harleysvi PA 1:04:43 2:11:58 2:10:25 9:58 2025 67 1084 John Kramer Jr

Migraine and Headache Relief Clinical studies and patient reports consistently show significant improvement in migraine frequency and severity