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Clin Obes 11(2):16
Can GLP-1 drugs help joint pain
For instance, both the FinnGen and UK Biobank datasets yielded consistent inverse associations for anxiety disorders (FinnGen: OR = 0.81, 95% CI [0.76, 0.87]
The semaglutide group had increased CTX-1, with an estimated difference of 166.4 g/L (p = 0.021), and reduced BMD in the lumbar spine (ETD: -0.018 g/cm
[16] [18] Alternative anxiolytic approaches that may be discussed with your GP include: Selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) as first-line pharmacological treatments for generalised anxiety disorder [15] [16] Cognitive behavioural therapy (CBT) or other evidence-based psychological interventions Gradual benzodiazepine tapering under medical supervision, potentially replacing alprazolam with longer-acting benzodiazepines before complete withdrawal Lifestyle modifications including regular exercise, sleep hygiene, and stress management techniques For weight management, if Wegovy proves intolerable, alternatives include other GLP-1 receptor agonists with different dosing schedules, orlistat (which works through a different mechanism), or comprehensive lifestyle intervention programmes
