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Functional and phenotypic analyses confirm the induction of a pancreatic endocrine fate, including positive dithizone (DTZ) staining indicative of insulin production, as well as the upregulation of key pancreatic markers such as Nestin , PDX-1 , paired box gene 4 ( PAX4 ), neurogenin 3 ( NGN3 ), Isl-1, MAFA, insulin, and glucose transporter 2 ( GLUT2 )

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Stability Data for LY3437943

Furthermore, the NMDAR antagonist kynurenic acid produced in the kynurenine pathway prevented these effects [65]

TB-500, Actin Sequestration & Cell Migration TB-500, the synthetic fragment of Thymosin Beta-4, is studied primarily for its actin-binding properties

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