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In relation to diabetes, CDC estimates show that 38.1 million adults or 14.7% of the US population had diabetes in 2021

Human G1 and G2 were inserted into a pFastDual plasmid and were prepared by insertion of His 6 -tagged human G 1 fragment (BamHI/HindIII site) under the polh promoter and insertion of G 2 fragment (XhoI/SphI site) under the p10 promoter, respectively (Genewiz)

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Yang M-J, Jia M, Cai M et al (2025) Central neuropeptides as key modulators of astrocyte function in neurodegenerative and neuropsychiatric disorders

Among the 36% of participants who had prediabetes at baseline, more than 95% reverted to normoglycemia with the 12 mg dose