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The drug actually has a long-standing FDA boxed warning that was reviewed in 2024 and remains a labeling formality, not a clinical concern at PCOS doses

Obtaining or using it outside these authorised settings may be unlawful and is unsafe

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For instance, liraglutide has been shown to enhance intracellular calcium levels in aortic endothelial cells, activating the CaMKK/AMPK axis to phosphorylate eNOS and CREB

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