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in the New England Journal of Medicine (N=338) demonstrated dose-dependent weight loss of up to 24.2% of body weight at 48 weeks in participants with obesity, compared to 2.1% in the placebo group 11
It also mitigated morphological changes in microglia, such as process retraction [94]
Published cosmetic studies have used concentrations in the low parts-per-million range to produce measurable fibroblast stimulation
2022, Coskun et al
Furthermore, a national cohort study found that a notable percentage of patients (up to 10%) required revisional surgery within 5 years of follow-up [16]
Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics
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