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administration of the experimental compounds (MK-801, GLP-1, GLP-1MK-801 (all at doses of 100 nmol kg 1 ), semaglutide (10 nmol kg 1 ) or isotonic saline as vehicle)

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Thus, mitochondria play a central role in the mechanisms of this form of programmed cell death [222]

It is likely that variations in experimental methods, biological systems, as well as the distinct metabolic characteristics of cells contributed to the variability in reported results 18,23

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