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A 2018 meta-analysis of 17 randomized controlled trials found that ALA supplementation significantly reduced total cholesterol, LDL-C, and triglycerides, though it had no consistent effect on HDL-C

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The mean age was 51.712.8 years, and the mean diabetes duration was 6 years at baseline

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Through the PI3K/Akt pathway, flavonoids promote myocardial cell survival by increasing resistance to oxidative stress and apoptosis, which is important for maintaining cardiac function ( 3.2.4 Anti-fibrosis activity Cardiac fibrosis is a condition in which there is excessive accumulation of extracellular matrix in the heart, leading to decreased elasticity and contractile function of the heart