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Yet one thing is abundantly clear: these agents have the potential to change how medicine is practiced

doi: 10.1078/0944-7113-00081 261 RituMNandiniJ

With that context in mind, here are some of the reasons a provider may consider a lower starting dose for certain individuals

Availability also varies by state

Prudence suggests checking baseline liver enzymes (ALT, AST, GGT) before starting either supplement and rechecking at 90 days, particularly if doses exceed 500 mg/day for either compound

This, in turn, reduces follicle-stimulating hormone (FSH) and luteinising hormone (LH) production, which are essential for ovulation and regular menstrual cycles