Am.,1990, 17(3), 601-612 15
Additionally, some individuals may have genetic variations in AMPK or NNMT expression that reduce responsiveness to these compounds, though this is less common
Do I have any health conditions that warrant professional evaluation before supplementation
Nutrients , 13(12), p.4359
If you experience any concerning symptoms while taking B12 supplements, report them to your healthcare provider and consider reporting suspected side effects via the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
Moreover, alcoholics may experience reduced intestinal absorption of vitamin B 12 (2), and individuals with acquired immunodeficiency syndrome (AIDS) appear to be at increased risk of deficiency, possibly related to a failure of the IF-B 12 receptor to take up the IF-B 12 complex (3)