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The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes
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A lower mortality in the GLP-1 RA group would expectedly lead to an underestimation of the fracture risk in that group, thereby exaggerating a protective effect of GLP-1 RAs
The injection day does not need to align with or avoid PPI dosing
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Subgroup analysis was done by stratifying studies by comparator groups (1) ALC monotherapy vs placebo
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