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Data availability All data underlying the findings of this study are available as supplementary files included in this publication

Fucoidan extract (FE) in combination with TAM has been reported with significant induction of cell growth inhibition, apoptosis, and cell cycle modification in MDA-MB-231 and MCF-7 cells (Zhang et al., 2013)

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doi:10.1097/00042737-200502000-00002 [PubMed] [Crosslink] 56

The response of the PPP, under these conditions, is due to the increased demand for NADPH by cells experiencing increased oxidative stress