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10 A conservative, well-chosen dose is needed to support systemic levels without overwhelming physiologic balance
Clinical trials such as the STEP program (semaglutide) and SURMOUNT trials (tirzepatide) have demonstrated improvements in physical functioning and quality of life scores, which patients often interpret as increased energy
Further investigation including a physical exam, stool and blood tests, scans, endoscopy and colonoscopy may be warranted
Lagenaur et al., 2021)
Injection site reactions are localized to a small area around the injection point and typically resolve within days
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