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Researchers isolated primary human chondrocytes (HCs) from the knees of healthy individuals and treated them with UA at two concentrations (6.25 M and 12 M) for 24 h

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Revealing the molecular mechanisms of efferent vagus nerve anti-inflammatory control have indicated the therapeutic applicability of 7nAChR agonists and centrally-acting acetylcholinesterase inhibitors, with first examples of clinical validation in clinical settings ( Fig

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Clinical trials have shown it can help people lose up to 15% of their body weightsignificantly more than those who took a placebo instead