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Can cause permanent tooth discoloration (typically yellow-gray-brown staining) or enamel hypoplasia (underdeveloped tooth enamel) if used during critical periods of tooth development, such as the last half of pregnancy or in children aged less than eight years

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Retatrutide is an unapproved investigational triple agonist (GLP-1, GIP, glucagon receptors) not licensed by the MHRA, EMA, or FDA for routine clinical use