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Addition of 2 M AT-2 or DTT served as calibration marks for fully reduced or oxidized roGFP2 for the calculation of the OxD, according to equation [1]

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TFA Removed: Minimized trifluoroacetic acid content to prevent cytotoxicity in sensitive primary cell lines

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In some cases, there may also be heart problems like dilated cardiomyopathy, which can progress to heart failure and death if not treated promptly with a substance called carnitine

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Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet

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