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Moreover, L-theanine could significantly inhibit the formation of neointima and prevent the transformation of VSMCs from contractile type to synthetic type in rat carotid artery balloon injury models (84)

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Additionally, in IPF lungs, mesenchymal progenitor cells (MPCs) display cancer-like features driven by a CD44/Brg1/PRMT5 axis, which epigenetically silences tumor suppressors RBL1 and PTEN, supporting self-renewal and fibrogenesis [93]