May 8 9 min read Updated: 21 hours ago If you are taking a GLP-1 medication like Wegovy or Zepbound, there is a good chance you have already thought about what happens when you stop
The most distinctive side effect is dysesthesia (skin tingling), affecting up to 20.9% of patients at the highest dose
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1,2 This restriction is based on animal studies where semaglutide and tirzepatide caused thyroid C-cell tumours in rats
Common Drug Interactions with GLP-1s Prescriptions to monitor include: Thyroid meds (like levothyroxine): delayed absorption = wonky labs Oral birth control : less reliable if not absorbed well (oops!) SSRIs/SNRIs : altered absorption can lead to mood changes Fat-soluble vitamins (A, D, E, K) : need bile flow and good digestion Iron/B12 : absorption requires stomach acid, which may be reduced PPIs (Prilosec, Nexium) : when combined with GLP-1s, can severely limit nutrient uptake Over-the-Counter Medications to Watch Even common OTC meds can cause problems when combined with GLP-1s
Enhances metabolic health and glucose regulation