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In mice bred to be deficient in mast cells (kit mutation), fibrosis and a-fib did not develop.[ref] Related article : Atrial fibrillation genes Mast cells are also implicated in the narrowing of the arteries due to atherosclerosis and play a role in stress-induced coronary artery disease

2) The results of the study performed by Wekwejt et al revealed several significant neurobehavioral changes in zebrafish exposed to a short-term HF diet and the subsequent ameliorative effects of MT-II treatment

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Clinical trials proving their effectiveness also included education on nutrition and physical activity, which are essential for achieving meaningful results