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Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans

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Inhibition of ROS by GSH or its analogs has been reported to block HIV replication, whereas increased intracellular GSH levels have been shown to enhance African swine fever virus replication 156,157 , indicating that the effect of GSH on viral replication varies according to the virus type

P4 plays a pivotal role in triggering polyploidization and the differentiation of the elongated fibroblastic stromal cells into rounded secreting decidual cells, thereby initiating the secretion of stromal factors such as prolactin (PRL) and insulin-like growth factor binding protein 1 (IGFBP1) to establish an immunotolerant and nutrient-rich environment essential for successful embryo implantation and pregnancy maintenance [4, 5]