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It does this by reducing the production or action of chemicals called prostaglandins, which are created in response to injury and certain diseases and conditions

Due to the above-mentioned effects of TZD on glycemic, hepatic metabolism, and inflammation, treatment with dual-agonism may reduce or reverse liver damage (lobular inflammation, hepatic steatosis, liver cell damage, and fibrosis) and metabolic dysfunction (35, 41)

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doi:10.1016/j.diabres.2004.02.004

Lightening skin injection and IV methods offer better bioavailability compared to oral supplements

Kameyama, M