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NAD+ serves as an essential coenzyme for hundreds of enzymatic reactions, including those involved in energy production, DNA repair, and cellular signaling
It also stimulates the liver to produce insulin-like growth factor 1 (IGF-1), which promotes tissue growth, supports protein synthesis, and contributes to overall metabolic regulation
Continued tirzepatide therapy sustained and even augmented initial weight loss, whereas discontinuation resulted in marked weight regain, confirming its durable effectiveness and good tolerability for long-term weight management (31)
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