doi: 10.1056/NEJMoa1607141 18 HolmanRRBethelMAMentzRJThompsonVPLokhnyginaYBuseJBet al
For example, patients taking tirzepatide have seen average weight reductions of up to 22.5% of their body weight, while those on semaglutide (at the weight management dose) have averaged around 15% weight loss
Additionally, GLP-1 medications are associated with gastrointestinal side effectsincluding nausea, vomiting, diarrhoea, and constipationwhich can affect nutritional intake and hydration status
Seek immediate medical attention if you experience severe, persistent abdominal pain (with or without vomiting) which could indicate pancreatitis, or symptoms of gallbladder disease such as right upper quadrant pain, fever, or yellowing of the skin
Mol Psychiatry 29 , 25872598 (2024)
GHSR-1a binding affinity and selectivity assays