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Although the significance of these findings for human cardiovascular disease is not yet clear, limited cell culture research suggested that organosulfur compounds from garlic could inhibit the proliferation and migration of VSMCs (39, 48, 49)

However, mechanistic insight into the interactions among sweeteners, xenobiotics, and gut bacteria remains limited, highlighting the need for accessible in vitro approaches to complement correlative analyses of fecal microbial communities and in vivo models

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