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For example, the frequency of spontaneous excitatory synaptic transmission (EPSCs) in the primary culture of hippocampal neurons of Mecp2 -KO mice was significantly decreased [376]
Ther Adv Neurol Disord
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Vigliante, I., Mannino, G., Maffei, M
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The involvement of GLP-1 in PD can be simplified to the activation of the MAPK/extracellular signal-regulated kinase 1/2 (ERK) pathway, which has an important role in synaptic plasticity, and the PI3K/Akt pathway signaled by GLP-1 receptor stimulation and the subsequent increase in cAMP and PKA and PI3K activation [73]
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